Sarcoidosis

Sarcoidosis is a disease involving abnormal collections of inflammatory cells that form lumps known as granulomas. The disease usually begins in the lungs, skin, or lymph nodes. Less commonly affected are the eyes, liver, heart, and brain. Any organ, however, can be affected. The signs and symptoms depend on the organ involved. Often, none, or only mild, symptoms are seen (engelska) WASOG World Association for Sarcoidosis and Other Granulomatous Disorders Sidan redigerades senast den 1 mars 2019 kl. 21.16. Wikipedias text är tillgänglig under licensen Creative Commons Erkännande-dela-lika 3.0 Unported. För bilder, se respektive bildsida (klicka på bilden). Se vidare. Sarcoidosis: treatments beyond prednisone and methotrexate. Expert Rev Respir Med. 2017 Mar;11(3):167-170. Länk Rossides M, Grunewald J, Eklund A, Kullberg S, Di Guiseppe D, Askling J, Arkema EV. Familial aggregation and heritability of sarcoidosis: a Swedish case-control study Sarcoidosis may be triggered by your body's immune system responding to foreign substances, such as viruses, bacteria, or chemicals. The areas of the body commonly affected by sarcoidosis. I: Sarcoidosis, Drent M, Costabel U. Eur Respir Monograph 2005; 32: 150-63. Darlington P, Tallstedt L, Padyukov L, Kockum I, Eklund A, Grunewald J. HLA-DRB1* alleles and symptoms associated with Heerfordt´s syndrome in sarcoidosis

Sarcoidosis is an inflammatory disease characterized by the development and growth of tiny lumps of cells called granulomas. If these tiny granulomas grow and clump together in an organ, they can affect the organ's structure and function.Overtime, this can lead to permanent scarring or thickening of the organ tissue (also called fibrosis). ). Although the granulomas can be found in almost any. Sarcoidosis is an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands. In people with sarcoidosis, abnormal masses or nodules (called granulomas. Sarcoidosis is a condition in which immune cells form lumps, called granulomas, in your organs. Inflammation is thought to cause granulomas to form and may lead to temporary or permanent scarring at the site of the granulomas. Your inherited genes or certain environmental factors may trigger the inflammation that leads to granulomas Sarcoidosis is a rare condition that causes small patches of red and swollen tissue, called granulomas, to develop in the organs of the body. It usually affects the lungs and skin. The symptoms of sarcoidosis depend on which organs are affected, but typically include

Sarcoidosis is a heterogeneous multisystem inflammatory disease of unknown cause characterized by the development and accumulation of noncaseating granulomata in any organ system.. Sarcoidosis occurs worldwide and affects people of all racial and ethnic backgrounds, but prevalence and severity are increased in African-American patients Sarcoidosis can be difficult to diagnose because the disease often produces few signs and symptoms in its early stages. When symptoms do occur, they may mimic those of other disorders. Your doctor will likely start with a physical exam and discuss your symptoms Sarcoidosis can affect the male reproductive system, particularly the testes, and may cause male infertility and erectile dysfunction. The disease rarely affects the female reproductive system. Sarcoidosis does not increase the incidence of fetal or maternal complications during pregnancy, unless it has caused severe impairment of the heart or. Sarcoidosis is an illness that causes tiny islands of inflammatory cells to form throughout the body. These microscopic groups of cells are called granulomas. They are especially common in the lungs, lymph nodes, skin, eyes and liver. The cause of sarcoidosis is unknown The Sarcoidosis Patient Compass is an interactive tool to help guide you through your sarcoidosis journey and help you understand which questions to ask your doctor. The working group that created the Sarcoidosis Patient Compass was led by SarcoidosisUK. Available to..

Sarcoidosis is a chronic disease that can affect multiple organs -- eyes, joints, skin -- but lungs are involved in 95% of cases. The disease is characterized by the buildup of immune system. Sarcoidosis is considered chronic in people whose disease remains active for more than 2-5 years; in this population sarcoidosis can be debilitating and life-threatening. It's estimated that the prevalence of sarcoidosis in the US ranges between 150,000 and 200,000 (Baughman, RP et al), with an estimated 1.2 million individuals with sarcoidosis worldwide (Denning, DW et al.

Sarcoidosis - Wikipedi

1. Sarcoidosis is a disease that leads to inflammation, usually in your lungs, skin, or lymph nodes. It starts as tiny, grain-like lumps, called granulomas. Sarcoidosis can affect any organ in your body. No one is sure what causes sarcoidosis. It affects men and women of all ages and races
2. Sarcoidosis mainly affects people between 20-40 years of age. White women are just as likely as white men to get sarcoidosis, but the black female gets sarcoidosis two times as often as the black male. No one knows what causes sarcoidosis. Sarcoidosis also appears to be more common and more severe in certain geographic areas
3. What is sarcoidosis? Sarcoidosis is a multisystem granulomatous disease. This means there are scattered collections of mixed inflammatory cells (granulomas) affecting many different parts of the body.Characteristically these are non-caseating epithelioid granulomas (a pathological description distinguishing sarcoidal granulomas from the caseating or cheese-like granulomas seen in tuberculosis)
4. Sarcoidosis can occur at any age, but commonly affects adults in their 30s or 40s. 4,833 individuals in our community survey told us their age. The data indicates that sarcoidosis is prevalent in all age groups - with 80% of cases being between 37 and 65. The average reported age was 50
5. Sarcoidosis is a condition in which abnormal nodules, called sarcoid granulomas, appear in the body's tissues. The lungs are most commonly affected, causing symptoms such as coughing and shortness of breath. Most people get better within one to three years and may not need any medical treatment other than close observation by their doctor
6. Sarcoidosis is a disease in which immune cells form small lumps, called granulomas, in your organs. Experts believe that inflammation causes these granulomas to form. The inflammation could be triggered by an infection or exposure to certain substances in your environment. Sarcoidosis is most common in the lungs, skin, or lymph nodes
7. Sarcoidosis is an inflammatory disease in which the immune system overreacts, causing clusters of inflamed tissue called granulomas to form in different organs of the body. Sarcoidosis most commonly affects the lungs and lymph nodes, but it can also affect the eyes, skin, heart and nervous system. Sarcoidosis is a rare disease

Sarkoidos - Wikipedi

Sarcoidosis must be differentiated from other diseases that cause granulomas, such as tuberculosis, histoplasmosis, and some other fungal infections. Treatment. Sarcoidosis may progress insidiously or rapidly or may remit as the result of treatment with corticosteroids Sarcoidosis is a multisystemic granulomatous disease that affects individuals worldwide. The lungs are most commonly involved but any organ can be involved. It has variable manifestations and clinical course. Diagnosis of sarcoidosis is based on clinicopathologic findings and the exclusion of other

Sarcoidosis is a condition in which inflammatory cells collect in tissues and organs. These cells form granulomas (lumps) in the lungs, skin, lymph nodes, or eyes. What increases my risk for sarcoidosis? The cause of sarcoidosis is not known. Sarcoidosis may be caused by an autoimmune disease Sarcoidosis is a granulomatous disease characterized by the presence of noncaseating granulomas in organs and tissue, such as the skin, lung, lymph nodes, eyes, joints, brain, kidneys, and heart. Cutaneous lesions may present with a variety of morphologies, including papules,.

Sarkoidos, pulmonell - Internetmedici

Sarcoidosis definition is - a chronic disease of unknown cause that is characterized by the formation of nodules especially in the lymph nodes, lungs, bones, and skin Sarcoidosis is a disease marked by an over-active immune system that leads to the formation of small clumps of inflammatory cells called granulomas in different tissues and organs, affecting how well they work. Over time, granulomas can become calcified or bone-like, and cause permanent damage. Because it can affect any organ, or multiple organs at the same time, sarcoidosis takes on different. Sarcoidosis is a rare condition that causes small patches of red and swollen tissue, called granulomas, to develop in the organs of the body. It usually affects the lungs and skin Sarcoidosis affects people in lots of different ways. It can cause symptoms in just one part of your body or many parts at the same time. Though sarcoidosis isn't always a lung condition, the lungs are affected in about 90% of cases. When the lungs are affected, it's called pulmonary sarcoidosis

Sarcoidosis: Causes, Symptoms, and Treatmen

1. Sarcoidosis is a multisystem, granulomatous disease. In this article, the various clinical manifestations, approach to, and management of, pulmonary and extrapulmonary sarcoidosis are reviewed
2. Sarcoidosis affects people of all racial and ethnic groups and occurs at any age, although usually before the age of 50 years. The incidence of sarcoidosis varies widely throughout the world, proba..
3. Sarcoidosis* / etiology Sarcoidosis* / therapy Sarcoidosis, Pulmonary / therapy Skin Diseases / drug therapy Substances Adrenal Cortex Hormones Grant support ES06538/ES/NIEHS NIH HHS/United States HL27353/HL/NHLBI NIH HHS/United States M01RR00051/RR/NCRR NIH.
4. In patients with sarcoidosis, COVID-19 can increase the risk for poor outcomes and death, which has resulted in the need for additional guidance on caring for these patients during the pandemic. An international team of pulmonary care specialists and researchers published a set of guidance statements on the management of sarcoidosis during the COVID-19 era in the journal, CHEST
5. Epidemiology. Sarcoidosis occurs all over the world in all ages and races. Attempts to describe accurate epidemiology are complicated by the use of inconsistent diagnostic criteria and variable (often asymptomatic) 9 disease manifestations. Still, certain epidemiological patterns are reported in the literature

Sarkoidos, extrapulmonell - Internetmedici

1. Skeletal sarcoidosis is an uncommon manifestation of sarcoidosis. Epidemiology Skeletal involvement is thought to occur in ~1-13% of patients with sarcoidosis 6,9. Osseous involvement may be more common in black patients 10. Clinical present..
2. Sarcoidosis is a rare condition that causes small patches of red and swollen tissue (granulomas) to develop in the organs of the body. It usually affects the lungs and skin. This condition may change the normal structure and possibly the function of an affected organ
3. Sarcoidosis leads to inflammation, which can affect the organs. Although in most cases the disease starts in the skin, lungs, or chest, sarcoidosis can affect any area of the body. New symptoms can show up at any time, so it is important for people with sarcoidosis to take care of themselves
4. Sarcoidosis is a multisystem disorder of unknown cause(s) which imposes a burden on patient's lives. Various aspects of sarcoidosis may account for this aggravating influence, such as the relatively young age at disease onset, the often chronic nature of the disease, the unpredictable course, and the broad range of often persistent symptoms
5. Sarcoidosis is a diagnosis of exclusion of granulomatous lung diseases, including tuberculosis and histoplasmosis. Typical history and biopsy from affected organs are essential for the diagnosis. Treated with topical corticosteroids for mild local cutaneous disease. Systemic corticosteroids are t..
6. Sarcoidosis is a disease that causes small masses of tissue clumps, called granulomas, to form inside the body. These granulomas can lead to damaged or malfunctioning organs in the body, and frequently involve the eyes. Uveitis (inflammation inside the eyes) is the most serious manifestation of sarcoidosis in the eyes
7. Define sarcoidosis. sarcoidosis synonyms, sarcoidosis pronunciation, sarcoidosis translation, English dictionary definition of sarcoidosis. n. pl. sar·coid·o·ses A disease of unknown origin that is characterized by the formation of granulomatous lesions especially in the lungs and lymph nodes of..

Sarcoidosis is a systemic disease of unknown cause that is characterised by the formation of immune granulomas in various organs, mainly the lungs and the lymphatic system. Studies show that sarcoidosis might be the result of an exaggerated granulomatous reaction after exposure to unidentified antigens in individuals who are genetically. Sarcoidosis is a disease that usually strikes in the lungs - although other organs such as the skin, the lymph nodes, the heart, the spleen, the liver, the pancreas, the eyes and the nervous. Sarcoidosis News is strictly a news and information website about the disease. It does not provide medical advice, diagnosis or treatment. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment Sarcoidosis is a rare disease caused by inflammation. It usually occurs in the lungs and lymph nodes, but it can occur in almost any organ. Sarcoidosis in the lungs is called pulmonary sarcoidosis. It causes small lumps of inflammatory cells in the lungs. These lumps are called granulomas and can affect how the lungs work Sarcoidosis is an inflammatory disorder resulting in noncaseating granulomas in one or more organs and tissues; etiology is unknown. The lungs and lymphatic system are most often affected, but sarcoidosis may affect any organ. Pulmonary symptoms range from none to cough, exertional dyspnea and, rarely, lung or other organ failure

Sarcoidosis Genetic and Rare Diseases Information Center

• Sarcoidosis-related granulomas are not different from granulomas that occur in other diseases. As a result, a complete physical exam and medical history - including occupational history, medication history, and environmental exposures - must be made before concluding that the illness is, in fact, sarcoidosis
• What is sarcoidosis. Sarcoidosis is a multisystem inflammatory disease of unknown cause that manifests by the formation of noncaseating granulomas, tiny clumps of inflammatory cells, in one or more organs of the body 1).When the immune system goes into overdrive and too many of these clumps form, they can interfere with an organ's structure and function
• Common symptoms of sarcoidosis such as cough and shortness of breath can mimic those of other diseases, but also can include skin rashes, joint pain and eye irritation. The exact cause of sarcoidosis is unknown, although there are some factors that increase risk
• Sarcoidosis, systemic disease that is characterized by the formation of granulomas (small grainy lumps) in affected tissue. Although the cause of sarcoidosis is unknown, the disease may be caused by an abnormal immune response to certain antigens. Sarcoidosis often disappears spontaneously withi

Sarcoidosis affects people uniquely, which in turn affects a person's individual treatment plan and prognosis. If you or a loved one has sarcoidosis, be sure to see specialists (e.g., a rheumatologist, a pulmonologist) who have experience working with patients with this inflammatory condition Sarcoidosis can sometimes be diagnosed solely on the basis of the symptoms, x-rays and blood tests but often, a biopsy of an involved organ tissue is required. If a biopsy is needed, your doctor will advise what the simplest and fastest form of biopsy is in your particular case

Sarcoidosis is a rare disease caused by inflammation. Sarcoidosis in the lungs is called pulmonary sarcoidosis. It causes small lumps of inflammatory cells in the lungs. These lumps are called granulomas and can affect how the lungs work Sarcoidosis is often treated with the help of a team of health care professionals. Because the disease can affect so many organs, you may work with health care providers who specialize in the treatment of the lungs, heart, brain, kidneys, liver, eyes, and skin

Sarcoidosis: Symptoms, Stages, Causes, Diagnosis, and

• Sarcoidosis is an inflammation of the lymph nodes in the chest. It is a benign condition most common in Caucasians or African-Americans in their 40s. Up to 7..
• Sarcoidosis is a condition where tiny lumps (nodules), known as granulomas, develop at various sites within your body, due to inflammation. It most commonly affects the lungs. However, it can affect almost any part of the body. The exact cause is not known. In many people, sarcoidosis goes away without any treatment
• Find sarcoidosis patient organisations across the globe where you can get support and information in your own language Patient compass. An interactive tool to help guide you through your sarcoidosis journey Treatment. If treatment is needed for the type of sarcoidosis you have, your doctor will discuss the options with you About this projec
• Sarcoidosis seems to be caused by an immune reaction continuing after the initial infection or causative antigen is cleared from the body. Sarcoidosis usually resolves without any medical intervention, but some cases become chronic or develop life-threatening complications
• Sarcoidosis is a condition in which groups of immune cells form small lumps called granulomas in multiple organs. Granulomas can develop anywhere in the body, but they commonly affect the lungs, skin, lymph nodes, and eyes
• Qué es . La sarcoidosis es una patología sistémica de origen desconocido. Se trata de una enfermedad que se caracteriza por la presencia de granulomas no caseificantes (formaciones nodulillares de carácter inflamatorio) benignos.. Síntomas . Sus manifestaciones clínicas suelen aparecer entre los 20 y los 40 años y puede afectar a cualquier órgano, siendo los pulmones, los ganglios.
• sarcoidosis (countable and uncountable, plural sarcoidoses) English Wikipedia has an article on: sarcoidosis. Wikipedia A multisystem disorder characterized by granulomas. 2007 May 25, Anthony Depalma, A Death Tied to 9/11 Dust Is Not Cause for Alarm to Others, Experts Say, in New York Times.

Video: Sarcoidosis NHLBI, NI

Sarcoidosis - NH

• Sarcoidosis largely affects patients in their mid-20s to mid-40s but cases do appear infrequently in younger and older patients. After the thorax, the skin and eyes are most commonly affected, followed by the liver (not usually clinically relevant), heart and nervous system
• Sarcoidosis is an inflammatory disease that can affect many of the body's organs including the lungs and lymph nodes. Learn more about sarcoidosis including its symptoms and treatment
• ed by the varying effects of several genes. There are various lines of evidence that would support this idea. First, there is variable prevalence and incidence in severity of the disease in individuals of different races and ethnic backgrounds
• Sarcoidosis Definition Sarcoidosis is a disease which can affect many organs within the body. It causes the development of granulomas. Granulomas are masses resembling little tumors. They are made up of clumps of cells from the immune system. Description Sarcoidosis is a very puzzling disorder. In addition to having no clear-cut understanding of the.
• Sarcoidosis is a systemic granulomatous disease of unknown cause affecting young and middle-aged adults. Patients commonly present with bilateral hilar lymphadenopathy, pulmonary infiltrates, and.
• Sarcoidosis is a disease in which abnormal collections of inflammatory cells (granulomas) form in many organs of the body. These collections of cells are most often found in the lungs, but granulomas may also form in the lymph nodes, lungs, liver, eyes and skin

Sarcoidosis - an overview ScienceDirect Topic

Sarcoidosis is a systemic disorder of unknown cause that is characterized by its pathological hallmark, the noncaseating granuloma. Its presenting features are protean, ranging from asymptomatic bu.. La sarcoidosis es una condición rara en la cual grupos de células inmunes forman masas, llamadas granulomas, en varios órganos del cuerpo. Se cree que la inflamación, que puede desencadenarse por infección o exposición a ciertas sustancias, juega un papel en la formación de granulomas

Sarcoidosis - Diagnosis and treatment - Mayo Clini

Sarcoidosis most often affects the lungs and its hilar lymph nodes but can also involve other areas of the body including the eyes, skin, sinuses, liver, kidneys, brain and heart. Sarcoidosis varies in how active and how severe it is for each person and over time Sarcoidosis is a chronic inflammatory condition which causes persistent granulomas. Its symptoms include fever, exhaustion, and pain that can affect any organ but most often affects the lungs. It. Sarcoidosis is a multisystem disease process of unknown etiology whose pathogenesis involves formation of an inflammatory lesion known as a granuloma. Histologically, noncaseating granulomas are prominent in biopsies from lymph nodes or affected organs Qué es. La sarcoidosis es una enfermedad de causa desconocida que se caracteriza por la inflamación de los ganglios linfáticos, los pulmones, el hígado, los ojos, la piel y otros tejidos.. En condiciones normales, el sistema inmunitario defiende al organismo de sustancias extrañas o nocivas, enviando, por ejemplo, células especiales

Sarcoidosis: Causes, Symptoms & Treatmen

• Sarcoidosis, also known as sarcoid or Besnier-Boeck disease, is a health condition involving the formation of small nodules known as granulomas at various sites of the body. It is thought to occur.
• Sarcoidosis is a systemic inflammatory disease of unknown etiology characterized by the formation of noncaseating granulomas. The disease most commonly affects the skin, lungs, lymph nodes, and eyes but can affect virtually any organ[1]. The first patient with confirmed sarcoid was described by dermatologist Jonathan Hutchinson in early 1880, whose skin lesions Hutchinson named Mortimer's.
• Sarcoidosis is considered as a multisystemic disease and chest physicians are frequently involved in the evaluation and management of this disease. The treatment of sarcoidosis ranges from nothing to complex immunosuppressive agents. Given the range of effective therapies for sarcoidosis, appropriate treatment is important

Sarcoidosis Guide: Causes, Symptoms and Treatment Option

• ority of patients the cutaneous manifestations are the primary organ system affected
• Sarcoidosis, a rare autoimmune disease characterized by inflammation in many parts of the body and often involves the lungs, is sometimes diagnosed years aft..
• Sarcoidosis can occur at any age, but has the highest incidence between 30-50 years of age. There is no described association between socioeconomic status and sarcoid incidence. There is a familial association, underscoring the presumed genetic predisposition for sarcoidosis,.
• Rarely, sarcoidosis can involve the heart or the brain (less than 1 in 20 of patients). Understanding the disease. Sarcoidosis is frequently a mild and self-limiting disease. Beware of medical text books and the internet. Both contain much true information but often they tend to focus on the most severe types of sarcoidosis
• Sarcoidosis or sarc is a multisystem disorder characterized by granuloma, ball-like encapsulations of phagocytic cells driven by microbes. Sarcoidosis is often called the great masquerader as there may be several atypical or nonspecific presentations - including not just the lungs but the brain, lymph glands, spleen, liver, skin and heart among others.
• Sarcoidosis can cause lumps, ulcers (sores), or areas of discolored skin. These areas may itch, but they don't hurt. These signs tend to appear on your back, arms, legs, and scalp. Sometimes they appear near your nose or eyes. These signs usually last a long time. Sarcoidosis may cause a more serious skin condition called lupus pernio

SarcoidosisUK - Information, Support, Research & Awarenes

Find out how the lung condition sarcoidosis is caused, the symptoms to look out for, how it is diagnosed and how it can be treated Moved Permanently. The document has moved here. Sarcoidosis. 1. Med Clin North Am. 2011 Nov;95(6):1223-34. doi: 10.1016/j.mcna.2011.08.004. Epub 2011 Oct 5. Sarcoidosis is a condition that causes inflammation in the body to result in bumps called granulomas forming on the skin, lymph nodes, in the lungs, eyes and sometimes in the heart and brain and other organs. For most people, their sarcoidosis prognosis is good Sarcoidosis is a multisystem inflammatory disease of unknown etiology that predominantly affects the lungs and intrathoracic lymph nodes. Sarcoidosis is manifested by the presence of noncaseating granulomas (NCGs) in affected organ tissues Sarcoidosis is the growth and accumulation of inflammatory-type cells in different parts of the body, most notably the lymph nodes, lungs, eyes and skin. The cells eventually form abnormal lumps or nodules (granulomas), which can change the structure and function of the tissue affected

Sarcoidosis is a disease characterized by a specific type of inflammation of various tissues of the body. Sarcoidosis can appear in almost any body organ, but it starts most often in the lungs or lymph nodes.As sarcoidosis progresses, microscopic lumps of a specific form of inflammation, called granulomas, appear in the affected tissues Sarcoidosis is a systemic inflammatory disease characterized by the formation of noncaseating granulomas in affected organs, most commonly the lungs, lymph nodes, skin, and eyes. The disease was first described in 1878 by noted surgeon Sir Jonathan Hutchinson as a dermatologic disorder Sarcoidosis is a multisystem granulomatous disease of unknown cause, that can affect almost any organ. The past decade we have gained more insights in the dysregulation of the immune system, which.

Sarcoidosis (from sarc meaning flesh, -oid, like, and -osis, diseased or abnormal condition), also called sarcoid, Besnier-Boeck disease or Besnier-Boeck-Schaumann disease, is a disease in which abnormal collections of chronic inflammatory cells (granulomas) form as nodules in multiple organs. [1] The cause of sarcoidosis is unknown. Granulomas most often appear in the lungs or the lymph nodes. Sarcoidosis remains a somewhat mysterious disease because many patients may enter spontaneous remission but some patients are chronically affected or relapse after intervention. Advances in recent sarcoidosis researches have added new insights to our understanding of complexity of sarcoidosis as introduced in this textbook,. Foundation For Sarcoidosis Research. 1820 W. Webster Ave., Ste 304 Chicago, Illinois 60614. Phone: 312-341-050 Sarcoidosis occurs when inflammatory cells or lumps form in the body. It most commonly affects the lungs or lymph nodes but also can affect any organ, including the heart. These lumps can make it difficult for your organs to function normally. Untreated sarcoidosis can result in organ damage Sarcoidosis definition, a disease of unknown cause, characterized by granulomatous tubercles of the skin, lymph nodes, lungs, eyes, and other structures. See more

Sarcoidosis affecting the eyes, heart, or kidneys is treated even when symptoms are mild because of the potentially serious risk of complications when these systems are involved. Current treatment is focused on improving symptoms, suppressing inflammation, reducing the impact of the granulomas, and preventing the development of lung fibrosis Sarcoidosis is a multisystem disease whose genesis is not yet completely known and that is characterized by noncaseating granulomas in the affected organs. The main manifestations of this disease occur in the lungs and the hilar lymph nodes.It is important to differentiate between acute sarcoidosis (which includes Löfgren's syndrome, a special form of the disease) and chronic sarcoidosis Sarcoidosis is a multi-organ disease with a variable clinical course. Although many patients experience disease resolution within a few years of diagnosis, some patients require long-term chronic therapy ().In addition, some patients develop chronic disease that may be refractory to conventional therapy and require cytotoxic or biological agents for disease control Sarcoidosis (Besnier-Boeck disease, Besnier-Boeck-Schaumann disease) is a multisystem inflammatory disease of unknown etiology, characterized by non-necrotizing granulomatous inflammation, predominantly in the lungs and intrathoracic lymph nodes. Sarcoidosis: Read more about Symptoms, Diagnosis, Treatment, Complications, Causes and Prognosis